Trazodone Side Effects

The documented risks of these drugs are provided so the public can make informed, educated decisions. Trazodone is an older antidepressant drug. The U.S. Food and Drug Administration warns that antidepressants can cause suicidal thinking and behavior in children and young adults. Trazodone is also known as Deprax, Desyrel, Molipaxin, Reslin, Trazolan, Trittico, Oleptro.

To see the total figures from IQVia on the number of people taking antidepressants in the U.S., click here.

Please note: No one should attempt to get off of psychiatric drugs without a doctor’s supervision. To help find medical practitioners in your area, click here.

Also, read the FDA’s Trazodone Medication Guide for more information. MedGuides include “the particular serious and significant public health concern that has created the need for the Medication Guide” and notes “pediatric risks.” (Note: Unfortunately, the FDA MedGuides only work on a desktop, not on a mobile device. Please complain to the FDA to make their public advisories accessible to all. 1-888-INFO-FDA or 1-888-463-6332.)



Trazodone Drug Warnings:

There have been five drug regulatory agency warnings from Ireland and the United States on trazodone. These include the following (note that some warnings cite more than one side effect, so the list below may not be equal to the total number of warnings):

2 warnings on trazodone causing suicide risk or suicidal behavior
1 warning on trazodone causing eye problems
1 warning on trazodone causing Serotonin Syndrome
1 warning on trazodone causing blood pressure changes or high or low blood pressure

Trazodone Drug Studies:

There have been 15 studies done in 10 countries (Brazil, Canada, France, Iran, Italy, Netherlands, Spain, Taiwan, United Kingdom and United States) on trazodone. These include the following (note that some studies cite more than one side effect, so the list below may not be equal to the total number of studies):

5 studies on trazodone causing suicide risk or attempts
3 studies on trazodone causing abnormal bleeding
2 studies on trazodone causing gastrointestinal problems
2 studies on trazodone causing skin conditions
1 study on trazodone causing sexual dysfunction
1 study on trazodone causing risk of fractures
1 study on trazodone causing self-harm
1 study on trazodone causing risk of falls
1 study on trazodone causing nervous system disorders
1 study on trazodone causing involuntary movements
1 study on trazodone causing diabetes
1 study on trazodone causing liver problems
1 study on trazodone causing allergic reactions
1 study on trazodone causing death or increased risk of death

Top Reactions for All Ages: There have been 1,228 adverse reactions reported to the US FDA in connection with Trazodone.

The FDA estimates that less than 1% of all serious events are ever reported to it, so the actual number of side effects occurring are most certainly higher.

  • 104 cases of priapism (persistent, usually painful erection)
  • 97 cases of completed suicides
  • 63 cases of dizziness
  • 62 cases of insomnia
  • 61 cases of the drug being ineffective
  • 55 cases of headaches
  • 47 cases of nausea
  • 46 cases of cardiac arrest
  • 45 cases of anxiety
  • 44 cases of serotonin syndrome


Documented Side Effects of Trazodone:
Source: Physicians Desk Reference, National Institutes of Health’s Medline Plus, and/or the drug label and package insert.

Aggressiveness
Agitation
Akathisia (psychomotor restlessness)
Anxiety
Blurred vision
Changes in appetite/weight
Confusion
Decreased ability to concentrate or remember
Decreased coordination
Difficulty breathing/ swallowing
Fainting
Hives
Hostility
Hypomania
Impulsivity
Insomnia
Irregular heartbeat

Irritability
Mania
Muscle pain
Nausea
Nervousness
Nightmares
Numbness, burning, or tingling in the arms, legs, hands, or feet
Panic attacks
Serotonin Syndrome
Suicidal thoughts/ behavior
Swelling of the face, hands, feet or lower legs
Uncontrollable shaking
Weakness or tiredness
Withdrawal symptoms


Note: Side effects of psychiatric drugs can persist for months, if not years, after stopping them.
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This brochure is a simple guide that documents the dangerous and deadly side effects of the drugs prescribed to millions of men, women and children diagnosed with bogus mental disorders.